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It is safe to drink alcohol in moderation whilst on azathioprine, but it may aggravate any nausea. You should avoid having 'live' vaccines such as polio and rubella. Most travel vaccines and flu vaccines are, however, acceptable. Discuss with your doctor or pharmacist first.
In the body, azathioprine is converted to mercaptopurine (6-MP) and thus has the same effects as that chemotherapy drug. They both are purine analogs that interfere with the metabolism of purine-based nucleotides found in DNA. ... The use of azathioprine results in killing cells such as T-lymphocytes.
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